What is Peripheral Neuropathy
Peripheral Neuropathy Symptoms
Types of Peripheral Neuropathy
Evaluation and Tests
Treatment and Therapy
Clinical Trials
Frequently Asked Questions
Center for Peripheral Neuopathy The University of Chicago
Quick Links About Us

Treatment and Therapy - Pain Medication

COX-2 Inhibitors

COX-2 inhibitors are a relatively new type of nonsteroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation by blocking a specific enzyme (COX-2) in the body. COX-2 inhibitors are less likely to cause gastrointestinal problems or bleeding than traditional NSAIDs (e.g., aspirin or ibuprofen) and may be a safer alternative for certain patients. However, because COX-2 inhibitors do not inhibit blood clotting (thin the blood), as do other NSAIDs — especially aspirin — they should not replace aspirin as a heart treatment.

COX-2 inhibitors include:

  • Celecoxib (Celebrex®)
  • Rofecoxib
  • Valdecoxib (Bextra®)

Home | Site Map | Search | Privacy | Disclaimers | Webmaster | UChicago | U of C BSD | U of C Hospitals

© 2023 The University of Chicago®