The goal of the research component of the Center is to promote multidisciplinary investigations into the etiology and pathogenesis of peripheral neuropathies. Research includes experimental studies to determine the molecular cause and eventual cure of these disorders. The Center research groups are primarily taking a molecular genetic approach to obtain a better understanding of the normal function, as well as dysfunction, of the peripheral nervous system. Over the past decade, as the DNA sequence of the human and mouse genomes has become known, the techniques associated with the identification and isolation of mutant genes in the mammalian genome have been dramatically improved. Furthermore, remarkable advances have been made in the development of quantitative approaches toward the molecular analysis of complex biological systems. In addition, since the ability to manipulate the mouse genome has become increasingly sophisticated, increasingly intricate mouse models can be generated. The research interest of the Center exploits these recent advances. The research team includes:
Brian Popko, Ph.D.
Jack Miller Professor in Neurological Diseases and Associate Chair for
Research, Department of Neurology
Director, Center for Peripheral Neuropathy
Raymond P. Roos, M.D.
Professor, Department of Neurology
Kamal Sharma, Ph.D.
Assistant Professor, Department of Neurobiology, Pharmacology & Physiology
Betty Soliven, M.D.
Associate Professor, Department of Neurology
Robert Wollmann, M.D., Ph.D.
Professor, Departments of Pathology and Neurology
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