|What is Peripheral Neuropathy|
|Peripheral Neuropathy Symptoms|
|Types of Peripheral Neuropathy|
|Evaluation and Tests|
|Treatment and Therapy|
|Frequently Asked Questions|
Types of Peripheral Neuropathy - Hereditary
Hereditary Neuropathy with Liability to Pressure Palsies (HNPP)
Hereditary neuropathy with liability to pressure palsies (HNPP) is a relatively common, though under-diagnosed, hereditary disorder in which a fairly mild pressure or trauma to a single nerve results in episodes or periods of numbness and weakness, similar to an arm or leg going to sleep. Unlike a limb going to sleep for a few seconds, each episode of numbness can last from several minutes to several days or months. The most common sites are the wrists, in conjunction with carpal tunnel syndrome, the elbows, and the knees. HNPP is inherited in an autosomal dominant manner, which means that each child of a person with HNPP has a 50% chance of inheriting the genetic mutation. It may be misdiagnosed as Charcot-Marie Tooth disease or Bell's palsy.
HNPP is a progressive hereditary disorder, but the symptoms can be so mild that they go unnoticed. For some people, there are years between episodes, while others have mild symptoms that progress at a steady rate.
There is no treatment other than symptomatic measures and avoiding positions that can create pressure such as leaning on elbows, crossing legs or ankles, or sitting for too long without changing position.
SYMPTOMS AND SIGNS
(Not all symptoms and signs may be present.)
EVALUATION AND TESTS
(Not all evaluation and tests may be necessary.)
TREATMENT AND THERAPY:
(Not all treatments and therapies may be indicated.)