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Treatment and Therapy - Pain Medication

Back to Antidepressants (as pain relievers)

Norepinephrine Reuptake Inhibitors (e.g. Wellbutrin®)

Norepinephrine reuptake inhibitors (NRIs) are a type of antidepressant medication that may reduce neuropathic pain. These drugs affect the nerve cells in the brain and inhibit the reuse of specific neurotransmitters (dopamine, serotonin, and norepinephrine), which may alleviate depression by achieving a chemical balance in the brain.

Examples of norepinephrine reuptake inhibitors are:

  • Bubropion (Wellbutrin®, Wellbutrin SR®)
  • Ludiomil (Maprotiline®)

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